Travel Vaccines and Advice for South Sudan

• Typhoid – Typhoid is a potentially serious bacterial infection caused by Salmonella Typhi. It spreads through contaminated food and water. To prevent it, practice good hygiene and consider vaccination when traveling to high-risk areas.
• Hepatitis A – Hepatitis A is a contagious liver infection caused by the hepatitis A virus, typically spread through ingestion of contaminated food or water, or close contact with an infected person. Symptoms include fatigue, stomach pain, and jaundice. The hepatitis A vaccine provides effective prevention against the virus. It is administered in a series of shots, usually starting in childhood, and is recommended for travel to areas with high infection rates.
• Yellow Fever – Yellow fever is a serious viral disease transmitted by infected mosquitoes, characterized by fever, jaundice, and bleeding. The yellow fever vaccine, given as a single injection, provides effective, long-term immunity against the virus. It’s recommended for people living in or traveling to endemic areas, often a travel requirement.
• Rabies – Rabies is a deadly viral disease that affects mammals and spreads through the saliva of infected animals, primarily through bites or scratches. Preventing rabies involves vaccinating pets, avoiding contact with wild animals, and seeking immediate medical attention if exposed. The rabies vaccine is a crucial preventive measure that stimulates the immune system to produce antibodies against the virus.
• Hepatitis B – Hepatitis B, a liver infection spread via infected fluids, can be prevented through safe practices and vaccination. The vaccine stimulates the immune system to produce antibodies, offering strong and enduring immunity against the virus.
• Meningitis – Meningitis is an inflammation of the membranes surrounding the brain and spinal cord, usually caused by viral or bacterial infections. Bacterial meningitis can be life-threatening. The meningitis vaccine protects against several types of meningococcal bacteria, reducing the risk of this serious condition. It’s recommended for certain age groups and travelers.
• Measles, Mumps, Rubella (MMR) – Measles, mumps, and rubella are highly contagious diseases with potentially severe consequences. Preventing their transmission is possible through vaccination with the MMR vaccine. This two-dose vaccine not only safeguards individuals but also helps create herd immunity, reducing the risk of outbreaks within communities.

South Sudan requires all travelers arriving to the country have proof of yellow fever vaccination. The CDC and WHO also recommend the vaccine for anyone who may be visiting the region.

Malaria is present in all regions of South Sudan. Travelers are advised to take antimalarials to protect themselves from infection. Atovaquone, doxycycline, mefloquine and tafenoquine are recommended for travelers to the region. Malaria parasites in South Sudan are resistant to chloroquine. Speak with your travel health specialist to identify which antimalarial is best for your trip and medical history.

Safeguard against bug bites by dressing appropriately and using EPA-registered repellents with DEET, picaridin, or OLE. If bitten, cleanse the area, refrain from scratching, and mitigate discomfort with OTC treatments. Seek medical aid for serious reactions.

When abroad, ensure food safety by avoiding street vendors, practicing hand hygiene, and opting for thoroughly cooked dishes. Choose bottled or canned drinks with intact seals. To prevent travelers’ diarrhea, maintain hand hygiene, avoid raw foods, and dine at trustworthy restaurants.

Altitude sickness, or acute mountain sickness (AMS), stems from inadequate oxygen at high elevations, causing symptoms like headaches and nausea. Preventing AMS involves gradual ascent, hydration, and potential medication use. Should AMS symptoms develop, swift descent to lower altitudes, rest, and medical evaluation are essential for recovery and safety.

• African Sleeping Sickness – African Sleeping Sickness, caused by parasites transmitted through tsetse fly bites in Africa, can be prevented by insect repellent, and avoiding fly-prone areas.
• African Tick-Bite Fever – In sub-Saharan Africa, African Tick-Bite Fever (ATBF) is transmitted by ticks. Stay safe by wearing protective clothing, using insect repellent, and checking for ticks.
• Crimean-Congo Hemorrhagic Fever – Crimean-Congo Hemorrhagic Fever, a severe viral illness, spreads through infected ticks and direct human contact with bodily fluids. Prevention includes tick avoidance, protective measures in healthcare settings, and the development of a potential vaccine to curb its transmission.
• Dengue – Dengue fever, caused by Aedes mosquito bites, poses a significant global health risk. Preventative measures, including avoiding mosquito bites, are crucial due to the lack of direct antiviral treatments.
• Ebola – Ebola is a severe disease transmitted through close contact with infected individuals or contaminated materials. Proper hygiene plays a crucial role in prevention, alongside avoiding infected individuals and healthcare infection control measures.
• Leishmaniasis – Infected sand flies are the primary vectors of leishmaniasis. Preventive measures include the use of insect repellents, protective clothing and staying indoors during sand fly peak hours.
• Mpox – Mpox, also known as monkeypox, is a viral illness originating from animals in Africa. Preventing monkeypox involves avoiding contact with possibly infected people or animals, practicing stringent hygiene, and considering vaccination against smallpox for potential cross-protection.
• Rift Valley Fever – Rift Valley Fever spreads through mosquito bites and contact with infected animal tissues. Vaccination of livestock, mosquito control, and public health education are key measures to prevent RVF transmission to humans.
• Schistosomiasis – Schistosomiasis is a parasitic infection transmitted through contaminated water. Avoiding contact with infected water sources and using protective clothing can reduce the risk of infection. Seeking medical evaluation promptly if symptoms such as fever and fatigue manifest enables timely diagnosis and treatment, preventing complications and promoting recovery.